Past Events

  • Dissertation Defense: "Development of a Scintillation Detector and The Influence on Clinical Imaging"

    DRL 4N30

    Joseph Panetta (UPenn)

  • Math-Bio seminar: "Decoding of pairwise coalescent times and detection of recent adaptation in biobank-scale SNP array data sets"

    318 Carolyn Lynch Laboratory

    Pier Francesco Palamara (Harvard School of Public Health)

    Coalescent hidden Markov models (HMM) such as the pairwise sequentially Markovian coalescent (PSMC, Li and Durbin, 2010) enable estimating the locus-specific posterior distribution of the time to most recent common ancestor (TMRCA) of a pair of haploid chromosomes when high-coverage sequencing data is available. I will present the “ascertained sequentially Markovian coalescent” (ASMC), a coalescent HMM that can be used to accurately estimate locus-specific TMRCA probabilities in widely available SNP array data.

  • Condensed Matter Seminar: "Geometry, frustration and force production in bacterial biopolymers"

    David Rittenhouse Laboratory, A4

    Ajay Gopinathan (University of California, Merced)

    Filamentous biopolymers in bacteria are involved in a variety of critical processes including templating cell growth, segregating genetic material and force production during motility and cell division. In this talk, I will discuss how a few of these systems translate biopolymer structure at multiple scales into physical function. At the molecular scale, the filamentous bacterial protein FtsZ converts chemical energy into mechanical constriction during cell division, but without the aid of any motor proteins.

  • Math-Bio seminar: "Mutations, genetic identity, and data granularity"

    318 Carolyn Lynch Laboratory

    Jun Li (University of Michigan)

    I will talk about two studies where new insights are gained after we work on a different level of data granularity. First, in collaboration with Sebastian Zoellner we analyzed ~36 million extremely rare variants (defined as singletons in ~4,000 individuals) uniformly ascertained in an as yet unpublished whole-genome sequencing dataset. Our goal is to estimate mutation rate variation across the genome, and to identify genomic and sequence-based predictors of such variation.

  • High Energy Seminar: "The Re-emergance of Spontaneously Broken Space-time Symmetries without Goldstones or Inverse Higgs"

    DRL 2N36

    Ira Rothstein (Carnegie Mellon)

    In this talk I will discuss how broken space-time symmetries can emerge in the IR after being spontaneously broken in the UV, even though there may be no Goldstone bosons. Given that there has been a large body of work on trying to get space-time symmetry (e.g. Lorentz) to be emergent in the IR via an RG attractive basin, this may seem like a very surprising and non-generic result.

  • Condensed Matter Seminar: "Invisibility, polarized light, and the eyes of giant squid: three tales of biological optics from the deep sea"

    David Rittenhouse Laboratory, A4

    Sonke Johnsen, Duke University

  • Astro Seminar: POSTPONED UNTIL FALL

    David Rittenhouse Laboratory, A4

    Zoltan Haiman (Columbia University)

    POSTPONED UNTIL FALL

  • Dissertation Defense: "Beyond Graphene: Monolayer Transition Metal Dichalcogenides, a New Platform for Science"

    Singh Building, Glandt Forum

    Carl Naylor (UPenn)

  • Advances in Biomedical Optics: "Theranostics Towards Point of Care Applications"

    Donner Auditorium, Basement, Donner Building, 3400 Spruce St.

    Israel Gannot (Johns Hopkins University and Tel-Aviv University)

    My lab has been active developing Theranostics methods that utilize the advantages of different modalities for a synergetic combination for optimized clinical treatment. A main theme of the lab is bringing the treatment to a point of care setting and preferably in outpatient clinics and even at home. We believe in a low cost, portable yet very powerful solutions to deliver good and effective healthcare treatment to various areas around the globe and in remote rural locations where high end very expensive instrumentations and methodologies are not affordable.

  • Department Colloquium: "Simulating the self-assembly of nano-puzzles"

    David Rittenhouse Laboratory, A8

    Daan Frenkel (Cambridge University) hosted by Tom Lubensky

    A holy grail of nano-technology is to create truly complex, multi-component structures by self-assembly. Most self-assembly has focused on the creation of "structural complexity." In my talk, I will discuss "Addressable Complexity": the creation of structures that contain hundreds or thousands of distinct building blocks that all must find their place in a 3D structure. Recent experiments have demonstrated the feasibility of making such structures. Simulation and theory yield surprising insights that can inform the design of novel structures and materials [1].