A representation of blood flow changes in a rat brain during cortical spreading depression. In the experiment, a large local concentration of KCl initiates a 'wave' of neuronal depolarization that propagates outward from a central point and then repeats itself. The figure shows images of blood flow in four parallel planes located within 3 millimeters of the skull.
Spatiotemporal heterogenous dynamics in air-fluidized grains near jamming. The colors represent the average speed over a time interval large enough for grain-sized rms displacement. The most mobile grains are in red, the least are in blue, across the rainbow. Note the stringy correlations of the mobile grains in red. From the lab of Prof. Doug Durian.
Carbon Nanotube FET Sensor
Schematic of a carbon nanotube FET sensor functionalized with an antibody to a Lyme disease biomarker protein. The insulating substrate is shown in pink. When antigen molecules bind to the antibody, the electrical characteristics of the FET are altered.
From the lab of Prof. Charlie Johnson.
Supernovae from the Sloan Digital Sky Survey
Part of the images of all the supernovae from the 2005-2007 observing campaigns of the Sloan Digital Sky Survey.
Nanoscale Electronic Nose
Prof. Charlie Johnson's group at Penn have coupled olfactory receptor proteins from mice to carbon nanotubes to create a prototype electronic nose. Olfactory receptors are embedded in nanodiscs that mimic the environment of the olfactory cell membrane. Odorant molecules bind to the receptor, which produces an electrical response in the carbon nanotube (gray cylinder).
Two University of Pennsylvania professors have won the chance to pursue their research full-time for the next academic year. The Simons Foundation has awarded fellowships to Mirjam Cvetic of the Department of Physics and Astronomy and Ron Donagi of the Department of Mathematics, both in the School of Arts and Sciences.
Prof. Randy Kamien has been named a 2013 Simons Investigator by the Simons Foundation. This appointment is in recognition of the promise of his research. The appointment comes with significant yearly research support as well as an annual fund for the department and a fund for indirect costs to the School of Arts and Sciences. This marks the second such award for the department in the first 2 years of the existence of the Simons Investigator awards.
The allure of personalized medicine has made new, more efficient ways of sequencing genes a top research priority. One promising technique involves reading DNA bases using changes in electrical current as they are threaded through a nanoscopic hole.
Now, a team led by University of Pennsylvania physicists has used solid-state nanopores to differentiate single-stranded DNA molecules containing sequences of a single repeating base.