Math-Bio seminar: "Decoding of pairwise coalescent times and detection of recent adaptation in biobank-scale SNP array data sets"
May 1, 2017 - 4:00 pm - 5:00 pm
318 Carolyn Lynch Laboratory
Pier Francesco Palamara (Harvard School of Public Health)
Coalescent hidden Markov models (HMM) such as the pairwise sequentially Markovian coalescent (PSMC, Li and Durbin, 2010) enable estimating the locus-specific posterior distribution of the time to most recent common ancestor (TMRCA) of a pair of haploid chromosomes when high-coverage sequencing data is available. I will present the “ascertained sequentially Markovian coalescent” (ASMC), a coalescent HMM that can be used to accurately estimate locus-specific TMRCA probabilities in widely available SNP array data.view more..
Dissertation Defense: "Development of a Scintillation Detector and The Influence on Clinical Imaging"
May 8, 2017 - 3:00 pm - 5:00 pm
Joseph Panetta (UPenn)
May 12, 2017 - 9:00 am - 5:00 pm
David Rittenhouse Laboratory, 4N12
May 19, 2017 - 9:00 am - 5:30 pm